Want to find the best supplement for your health?

MSM is one of many naturally occurring sulfur compounds that can deliver tremendous health benefits. But with so many brands out there, it’s not always easy to know which ones are worth the investment. That’s why we put together this comprehensive review of seven top-tier MSM supplements – so you have all the information needed to make a well-informed decision.

Whether you're looking for an immune system booster, improved joint and muscle function, or other general health improvements, these reviews provide a complete breakdown of each product's efficacy, ingredients list, dosage instructions, and user reviews - making sure you get maximum value from every purchase.

How We Picked These Products

Finding the right and most effective MSM supplement can be an overwhelming task. With so many options out there, it’s hard to know what to choose.

Not only is there a lot of conflicting information out there, but each company's formula and ingredients vary wildly—leaving you feeling lost and confused about which one will give you the best results.

That’s why we did all the research for you and compiled the ultimate list of 7 carefully curated MSM supplements that guarantee maximum health benefits. Stop wasting your time trying to find the perfect supplement—go with one of our top 7 picks today!

Best Organic MSM Supplement That Improve Overall Health

No Boundaries Organic Sulfur Supplement 

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Why It's Our Favorite

No Boundaries MSM organic sulfur supplement is recognized for its ability to improve overall health. From supporting pain and physical function to treating arthritis and alleviating symptoms of allergic rhinitis, this supplement offers a comprehensive approach to well-being.

Maintaining healthy skin and complexion, increasing flexibility, hair, and nail health, and detoxifying the body are just a few of the benefits that can be attributed to MSM sulfur. Consumption of MSM has also been linked to an increase in the production of glutathione, an important antioxidant that protects cells from damage.

The sulfur content in MSM can also stimulate connective tissue production and provide support for joints, resulting in a decrease in joint pain and stiffness.

Things To Keep In Mind

This organic sulfur offers a range of benefits from detoxification to improved joint health, and it can also help alleviate symptoms caused by a deficiency in this vital nutrient. By choosing No Boundaries Health and Wellness, you'll receive 99.9% pure sulfur crystals that are approved after a pilot clinical trial and known to increase energy levels, improve skin, hair, and nail health, and even combat the effects of joint pain and stiffness.

Best MSM Supplement That Features High-Quality OptiMSM

Doctor's Best MSM Supplement

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Why It's Our Favorite

Doctor's Best MSM supplement features high-quality OptiMSM and offers excellent support for healthy connective tissues and overall joint mobility. This natural sulfur compound has been extensively studied for both its safety and efficacy, making it a trusted choice among health enthusiasts.

MSM may also help reduce oxidative damage in the body, thereby bolstering a healthy immune system. With Doctor's Best MSM supplement, you can have confidence in a product that adheres to stringent quality standards and is formulated with your well-being in mind.

Whether you're an athlete seeking to support joint health or simply aiming for overall wellness, Doctor's Best MSM supplement with OptiMSM might just be the solution you've been searching for.

Things To Keep In Mind

Doctor's Best MSM supplement offers exceptional benefits for individuals seeking to enhance their immune response, treat arthritis, and safeguard their bodies against harmful toxins and free radicals. In addition to fortifying immune function, MSM is widely recognized as "nature's beauty mineral" due to its remarkable ability to enhance the health of the skin, hair, and nails.

Sulfur, a key component of MSM, serves as a vital building block for promoting the production of healthy collagen and the synthesis of keratin. For those aiming to bolster their immune system and nurture overall well-being, Doctor's Best MSM supplement presents an excellent choice.

Through its potent combination of immune-supporting properties and beauty-enhancing effects, MSM emerges as one of nature's most invaluable resources.

Best MSM Supplement with A Smarter Formula

Jarrow Formulas MSM Supplement 

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Why It's Our Favorite

Jarrow Formulas MSM supplement stands as a testament to intelligent design, driven by robust scientific research. Available in the form of veggie capsules, this supplement extends its embrace to both vegans and vegetarians.

Each capsule is carefully formulated to ensure the comprehensive delivery of the full spectrum of benefits derived from essential vitamins and minerals. The incorporation of vegetarian-friendly capsules not only champions inclusivity but also empowers you to seamlessly integrate this MSM supplement into your daily regimen, in alignment with your dietary choices.

Things To Keep In Mind

This supplement is thoughtfully designed to provide optimal benefits. The ideal daily dosage, ranging from one to three times a day, should be determined in consultation with qualified healthcare professionals.

The incorporation of veggie capsules not only caters to a wide array of dietary choices but also underscores the brand's commitment to inclusivity. By prioritizing guidance from healthcare experts, Jarrow Formulas ensures a secure and individualized consumption approach.

Beyond the product's formulation, Jarrow Formulas demonstrates an unwavering dedication to holistic well-being, fusing scientific rigor, dietary versatility, and expert guidance to create a truly comprehensive wellness experience.

Best MSM Supplement for Joint Support

Life Extension MSM Supplement 

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Why It's Our Favorite

Life Extension supplement features a transformative solution that promises enhanced joint support and overall health. With a focus on optimizing joint health, this supplement incorporates the renowned benefits of MSM (Methylsulfonylmethane) to offer a unique approach to promoting joint comfort, mobility, and function.

Clinical studies have showcased MSM's remarkable ability to inhibit inflammation, making it a potent ally for fostering joint vitality. What's even more remarkable is its synergistic partnership with popular joint health compounds like glucosamine and chondroitin.

But Life Extension's innovation doesn't stop there; it also provides benefits to support post-workout recovery and healthy muscle structure, effectively combating exercise-induced oxidative stress.

Things To Keep In Mind

Life Extension supplement comes to the forefront with a resounding emphasis on ingredient quality. Meticulously sourced using only the finest raw materials, this supplement embodies the purity and potency that your body rightfully deserves.

Demonstrating an unwavering commitment to excellence, this product proudly holds certifications for being non-GMO and gluten-free, ensuring a conscious and comprehensive approach to your well-being. Manufactured within the United States, each supplement undergoes rigorous testing, and a certificate of analysis accompanies every product, providing you with the assurance of its superior quality.

Over four decades of dedicated work have shaped Life Extension's commitment to advancing health. Their formulations are not mere products; they are the result of years of scientific exploration and innovation.

Best MSM Supplement That Is Professionally Crafted

Horbaach MSM Supplement

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Why It's Our Favorite

Horbaach MSM Supplement is professionally crafted and is the perfect addition to your daily routine for anyone looking for high-level support for their active lifestyle. With 3,000 mg of MSM in each serving, this supplement is made to ensure purity, potency, and maximum daily support.

Horbaach prioritizes laboratory testing and trusted ingredient sourcing to produce superior-quality supplement that guarantees 100% satisfaction. This supplement is entirely free of wheat, yeast, milk, lactose, soy, artificial color, and flavor, making it add all of the benefits to your daily routine without additives.

Things To Keep In Mind

This MSM supplement is known to be of therapeutic grade and ethically sourced. This signifies that this supplement is free from contaminants, and they are sourced from natural ingredients to highlight their therapeutic benefits. Particularly if you are pregnant, nursing, taking any medications, or have any medical condition.

In the unlikely event of experiencing any adverse reactions, it is recommended to discontinue use and contact your doctor immediately. The commitment to providing therapeutic-grade MSM supplements aligns with Horbaach's ethos of empowering customers to achieve wellness goals through quality and innovative products.

Best MSM Supplement That Comes In Advanced 8-In-1 Formula

Viva Naturals MSM Supplement

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Why It's Our Favorite

Viva Naturals MSM supplement comes into the picture with its advanced 8-in-1 formula formulated to support the 5 crucial signs of joint health: mobility, flexibility, strength, lubrication, and comfort.

It contains a potent blend of MSM, glucosamine, chondroitin, turmeric, ginger, Boswellia extract, hyaluronic acid, and collagen peptides - all of which work together to promote the overall health and well-being of our joints and cartilage, treating arthritis and addressing joint degeneration.

The MSM contents help reduce inflammation and pain, while the glucosamine and chondroitin provide the necessary building blocks for healthy cartilage formation. Turmeric and ginger have natural anti-inflammatory properties, and Boswellia extract supports healthy blood flow and mobility. The inclusion of hyaluronic acid and collagen peptides provides added joint lubrication, cushioning, and strength.

Things To Keep In Mind

The Viva Naturals MSM supplement arrives in a convenient unflavored capsule format, making it a hassle-free addition to your daily routine. With a generous unit count of 90 capsules and a weight of 4.7 ounces, this supplement not only offers ease of consumption but also ensures practical storage.

Its compact size makes it effortlessly portable, enabling you to maintain your wellness regimen even on the go. What sets this supplement apart is its incorporation of special ingredients, including glucosamine, known for their potential to contribute to joint health, alleviate muscle soreness, and address joint degeneration.

Best MSM Supplement That Provides Healthy Immune Function

Pure Encapsulations MSM Supplement 

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Why It's Our Favorite

Pure Encapsulations MSM Supplement is a naturally derived sulfur formula that supports joint functionality and comfort, specifically connective tissue health. The sulfur compound also provides potential support for healthy immune function.

Methylsulfonylmethane, or dimethyl sulfone, has the ability to enhance the body's ability to fight off harmful pathogens and boost overall immune function. Moreover, sulfur supports tissue containing significant amounts of collagen and keratin, including hair and skin.

Things To Keep In Mind

What sets this supplement apart is the rigorous process used to create it. Only premium ingredients are sourced from trusted suppliers and guided by nutritional experts, ensuring a top-quality supplement. The manufacturing and testing process is also carefully monitored to verify potency and purity.

Now here is the best part: This supplement is designed to be inclusive and is completely free from common allergens, artificial colors, flavors, sweeteners, and unnecessary binders, fillers, and preservatives. By eliminating these potentially harmful ingredients, this supplement not only works wonders but can also be safely used by anyone with dietary restrictions.


Navigating the world of MSM supplements can be confusing and overwhelming. There are so many choices and even more opinions about which products are the best.

It can be difficult to separate fact from fiction when it comes to understanding what's actually in a particular supplement and how much you should take as part of your daily routine.

That's why we included the FAQs about the MSM Supplements page. This page will feature all the most asked questions and provide you with reliable, comprehensive info so that you can make an informed decision about which product is right for your needs.

What does taking MSM do for you?

Taking MSM (Methylsulfonylmethane) has a variety of possible health benefits. The most common reasons people take it are joint pain, inflammation, allergies, and skin health. It is also used to reduce muscle cramps and fatigue. MSM may also help with stimulating collagen production in the body.

What does MSM do to hormones?

MSM has been found to have an effect on hormones in the body as it can help balance cortisol levels and improve hormone sensitivity. Studies suggest that these effects could be beneficial for improving symptoms related to PMS and menopause. More research is needed on this topic though to further understand its impact on hormones in the body.

Is MSM collagen?

No, MSM is not collagen. Collagen is a structural protein found in the body that gives skin its strength and elasticity. MSM is an organic sulfur compound that helps to increase cell permeability and improve nutrient absorption. While they both have beneficial effects on the body, their functions are different.

When should I take the MSM supplement?

It’s recommended that you start at a lower dose and monitor how your body responds before slowly increasing the dosage over time if necessary. For many people, one to two capsules per day is where they settle in and find a good balance. When it comes to taking MSM (methylsulfonylmethane), the best advice is to always check with your doctor first.

Is it OK to take MSM daily?

It’s okay to take MSM every day if recommended by your doctor; however, depending on your individual physiology some people may experience side effects including diarrhea or nausea. Long-term ingestion of high doses can also cause kidney damage. 

So it’s important to speak with a medical professional before consuming large amounts for extended periods of time and wean off gradually when finished taking MSM. Make sure you're not taking any other complementary and alternative medicine as it can mix up things.

Does MSM help hair growth?

Yes, MSM (Methylsulfonylmethane) can help with hair growth. MSM is a naturally occurring sulfur compound that has many beneficial effects on the body, including promoting healthier-looking hair. The sulfur in MSM helps stimulate collagen production which is essential for strong and healthy hair growth.

Sulfur also helps improve blood circulation to the scalp, which encourages stronger roots and faster growth of new strands of hair. In addition, several studies have indicated that MSM could keep dandruff at bay by reducing skin inflammation and dryness.

Does MSM improve skin?

Yes, MSM can improve skin health as well! Since it contains sulfur compounds which are important components of connective tissue like collagen and keratin, supplementing with MSM could support healthy skin tissue formation by supplying adequate levels of these nutrients to the cells in the dermis layer where skin elasticity resides.

When taken orally or applied topically as a cream or lotion, it has been found to reduce wrinkles while boosting hydration levels for a more youthful complexion overall.

Does MSM increase collagen?

Yes, MSM (methylsulfonylmethane) can potentially increase collagen levels in the body. It is a sulfur-rich compound found naturally in many plants and has long been used as an aid to reduce inflammation and improve joint health. Studies show that MSM helps to activate chondrocytes, which are cells responsible for producing collagen.

What is MSM in vitamins?

MSM, or methylsulfonylmethane, is a naturally occurring sulfur compound found in certain foods and available as a dietary supplement. It’s an organic form of sulfur that helps to maintain many important bodily functions, including joint health, skin health, immune system health, and more. MSM works by helping your body metabolize proteins into amino acids that are necessary for the repair and growth of cells.

How much is MSM recommended daily?

The recommended daily amount of MSM depends on your individual needs. 1-2g per day is sufficient for most people; however, people with more serious medical issues may need up to 6-8g. It’s always best to consult with your medical expert before starting any new supplement regimen especially if you're taking any alternative and complementary medicine side by side.

How does MSM affect the brain?

MSM can have beneficial effects on the brain because it helps to increase circulation and improve communication between neurons which improves cellular metabolism and energy production in the brain. 

Studies have also shown that MSM can help improve memory formation and recall as well as enhance overall cognitive performance – making it great for those looking to boost their mental acuity!

How much vitamin C should I take with MSM?

It's recommended that you take at least 50mg of vitamin C along with MSM supplements since Vitamin C plays an important role in helping the body convert sulfate molecules into usable fatty acid chains which provide fuel for cells throughout the body – including brain cells! 

The combination of Vitamin C + MSM makes this process go even more smoothly resulting in improved cell maintenance over time – leading to increased physical & mental performance gains overall!

Can I take MSM and magnesium together?

Yes, you can take MSM (Methylsulfonylmethane) and magnesium together. In fact, they can complement each other's benefits. MSM is known for its potential to reduce inflammation and promote joint health, while magnesium is essential for muscle and nerve function. Combining them might provide a dual advantage: MSM could help alleviate inflammation while magnesium acts as a muscle relaxant.

What vitamins cannot be mixed with magnesium?

Vitamins B6 and C should not be taken at the same time as magnesium, as they can interfere with magnesium absorption. In addition, some calcium supplements may also interact with magnesium. Taking too much of certain vitamins or minerals can lead to a host of health problems, so it's important to make sure you’re taking the right doses for your body.

Summing Up

MSM supplements have become increasingly popular in recent years, and it’s no surprise. With a plethora of health benefits linked to them, ranging from helping to relieve joint pain to better mood balance to treating seasonal allergic rhinitis, their popularity is hardly surprising.

From the 7 best MSM supplements that we have reviewed, each has something unique to offer its users and surely, they come out after clinical and instrumental evaluation. Whether you’re seeking an all-around comprehensive product or one fitted with specific benefits, there’s sure to be an option that follows your needs. Whoever took MSM reported feeling better from symptoms.

As always, conversing with professionals prior to beginning any supplement routine can help you make the best decision for your health and well-being. Taking these simple steps towards a healthier lifestyle is sure to give you long-lasting results. So consider stocking up on one of these 7 best methylsulfonylmethane MSM dietary supplements today!